Treatment
After removal of the corneal epithelium riboflavin/dextran solution is instilled for 30 minutes (1 drop every 2 minutes).

Application of the riboflavin/dextran solution after removal of the epithelium.
Then the corneal penetration of riboflavin/dextran solution is checked under a slit lamp by establishing that the anterior chamber is slightly yellow. Pachymetry is performed to make sure that minimum corneal thickness is maintained. (Otherwise the cornea is swollen with Innocross - RTM Hypotonic solution to achieve at least a corneal thickness of 400 μm).

Slit lamp check of the riboflavin penetration. The anterior chamber has to be slightly yellow.
UV-A irradiation starts using the UV-XTM device from IROC Innocross under continued administration of riboflavin/dextran solution (1 drop every 2 minutes). After 30 minutes (UV-XTM 1000) or 10-12 minutes (UV-XTM 2000) of radiation the treatment is finished and the patient receives post-op treatment like after PRK: bandage contact lens, painkiller, steroids, antibiotics, artificial tears.

UV-A illumination of the cornea using the UV-XTM device from IROC Innocross.